Neuroanatomy of memory.

نویسندگان

  • S Zola-Morgan
  • L R Squire
چکیده

Three important developments have occurred in the area of memory during the past decade. The first was the recognition that there is more than one kind of memory (Cohen 1984; Schacter 1987; Squire 1982; Tulving 1985). Declarative memory (or, explicit memory) affords the capacity for conscious recollections about facts and events. This is the kind of memory that is usually referred to when the terms "memory" or "remembering" are used in ordinary language. Declarative memory can be contrasted with nondeclarative (or implicit) memory, a heterogeneous collection nonconscious abilities that includes the learning of skills and habits, priming, and some forms of classical conditioning. In these cases, experience cumulates in behavioral change, but without affording access to any memory content. The distinction between declarative and nondeclarative memory is fundamental, because it has turned out that different kinds of memory are supported by different brain systems. The second important development was the establishment of an animal model of human amnesia in the monkey (Mahut & Moss 1984; Mishkin 1982; Squire & Zola-Morgan 1983). In the 1950s, Scoville & Milner (1957) described the severe amnesia that followed bilateral surgical removal of the medial temporal lobe (patient H.M.). This important case demonstrated that memory is a distinct cerebral function, dissociable from other perceptual and cognitive abilities. Subsequently, surgical lesions of the medial temporal lobe in monkeys, which approximated the damage sustained by patient H.M., were shown to reproduce many features of human memory impairment. In particular, both monkeys and humans were

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عنوان ژورنال:
  • Annual review of neuroscience

دوره 16  شماره 

صفحات  -

تاریخ انتشار 1993